বাংলায় দেখুন

Serontin

Syrup

🧬 Ethosuximide 🏢 ACI Limited

Generic Name Ethosuximide

Strength 250 mg/5 ml

Manufacturer ACI Limited

Unit Price 70 ml bottle: ৳ 130.39

70 ml bottle: ৳ 130.39 ✅ In Stock per unit · Bangladesh

🛒 Buy Now

🔒 Secure checkout · Return & Refund Policy

🔹 Indications নির্দেশনা

Serontin is indicated for the control of absence seizures.

🔹 Pharmacology ফার্মাকোলজি

Ethosuximide suppresses the paroxysmal three cycle per second spike and wave activity associated with lapses of consciousness which is common in absence (petit mal) seizures. The frequency of epileptiform attacks is reduced, apparently by depression of the motor cortex and elevation of the threshold of the central nervous system to convulsive stimuli.

🔹 Dosage & Administration

Pediatric Patients-

Children 3 to 6 years of age: Initially 5 ml (250 mg) daily in a single dose
Children ≥6 years of age: Initially 10 ml (500 mg) daily in a single dose or divided doses
Dosage should be increased by small increments, by 5 ml (250 mg) every 4–7 days until seizure control is achieved with minimal adverse effects. Dosage usually should not be >30 ml (1.5 g) daily, given in divided doses. If dosage is >1.5 g daily, clinical must closely supervise patients.
Usual maintenance dosage: 20 mg/kg or 1.2 g/m2 daily

Adults-

Initially 10 ml (500 mg) daily in a single dose or divided doses
Dosage should be increased by small increments, by 5 ml (250 mg) every 4–7 days until seizure control is achieved with minimal adverse effects. Dosage usually should not be >30 ml (1.5 g), given in divided doses.
Usual maintenance dosage: 20 mg/kg or 1.2 g/m2 daily

🔹 Interaction মিথস্ক্রিয়া

The plasma concentrations of Serontin may be reduced by carbamazepine, primidone, phenobarbitone and lamotrigine and increased by isoniazid. No consistent changes in levels of Serontin occur when used in combination with phenytoin or sodium valproate. Phenytoin levels however are increased by concomitant Serontin.

🔹 Contraindications

Ethosuximide should not be used in patients with hypersensitivity to succinimides (e.g. methosuximide, phenosuximide) & known hypersensitivity to the active substance or to any of the excipients.

🔹 Side Effects

The common side effects of Serontin are gastro-intestinal disturbances including nausea, vomiting, diarrhoea, abdominal pain, anorexia, weight loss. The less frequent side effects are headache, fatigue, drowsiness, dizziness, hiccup, ataxia, mild euphoria, irritability, aggression, impaired concentration; rarely tongue swelling, sleep disturbances, night terrors, depression, psychosis, photophobia, dyskinesia, increased libido, vaginal bleeding, myopia, gingival hypertrophy, and rash; hyperactivity, increase in seizure frequency, blood disorders such as leucopenia, agranulocytosis, pancytopenia, and aplastic anaemia, systemic lupus erythematosus, and Stevens-Johnson syndrome.

🔹 Pregnancy & Lactation

Ethosuximide crosses the placenta. Risk-benefit ratio should be weighed in treating or counseling epileptic women of childbearing potential. Ethosuximide is excreted in breast milk. It should be used in nursing mothers only if the benefits clearly outweigh the risks. Breast feeding is best avoided.

🔹 Precautions & Warnings সতর্কতা

Serontin should be used with caution in hepatic or renal impairment. Serontin may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks such as driving or other such activities requiring alertness. Therefore, the patient should be cautioned accordingly. Abrupt withdrawal should be avoided. Patients should be monitored for signs of suicidal ideation & behaviors and appropriate treatment should be considered.

🔹 Storage Conditions সংরক্ষণ

Keep away from the reach of children. Store in a cool and dry place protected from light.

🔍 People also search for

Serontin Serontin Syrup used for Serontin side effects Serontin price Serontin dose Serontin Syrup uses Is Serontin safe Serontin dosage Serontin alternative Serontin Bangladesh Ethosuximide Ethosuximide price Bangladesh Syrup price Bangladesh ACI Limited medicine bd Serontin 250 mg/5 ml Serontin 250 mg/5 ml price

💡 Frequently Asked Questions

Serontin is indicated for the control of absence seizures.

Pediatric Patients- Children 3 to 6 years of age: Initially 5 ml (250 mg) daily in a single dose Children ≥6 years of age: Initially 10 ml (500 mg) daily in a single dose or divided doses Dosage should be increased by small increments, by 5 ml (...

User Reviews

⭐

No reviews yet!

Be the first to share your experience.