- Sedatives
- Hypnotics for the short-term treatment of insomnia
- Pre-anesthetics
- Long-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures. And, in the emergency control of certain acute convulsive episodes, (those associated with status epilepticus, eclampsia meningitis, tetanus, and toxic reactions to Strychnine or local anesthetics).
💊
Phenoson
Tablet
Generic Name
Phenobarbital
Strength
30 mg
Manufacturer
Jayson Pharmaceutical Ltd.
Unit Price
Unit Price: ৳ 0.78 (10 x 10: ৳ 78.00) Strip Price: ৳ 7.80
Unit Price: ৳ 0.78 (10 x 10: ৳ 78.00) Strip Price: ৳ 7.80
✅ In Stock
per unit · Bangladesh
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🔹 Indications
Phenoson is indicated for the following conditions:
🔹 Pharmacology
Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal). Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. This has the effect of elevating seizure threshold and reducing the spread of seizure activity from a seizure focus. Phenobarbital may also inhibit calcium channels, resulting in a decrease in excitatory transmitter release. The sedative-hypnotic effects of phenobarbital are likely the result of its effect on the polysynaptic midbrain reticular formation, which controls CNS arousal.
🔹 Dosage & Administration
Suggested doses of Phenobarbital for specific indications are as follows:
Pediatric Oral Dosage:
Pediatric Oral Dosage:
- Preoperative: 1 mg to 3 mg/kg.
- Anticonvulsant: 1 mg to 6 mg/kg per day
- Daytime sedative: 30 mg to 120 mg daily in 2 to 3 divided doses.
- Bedtime hypnotic: 100 mg to 320 mg.
- Anticonvulsant: 50 mg to 100 mg 2 to 3 times daily.
- 15 to 20 mg/kg IV over 10 to 15 min.
- Preoperative Sedation:1 to 3 mg/kg IM/IV;
- Anticonvulsant: 4 to 6 mg/kg IM/IV per day, for 10 days. Alternatively, use 10 to 15 mg/kg IM/IV per day to reach therapeutic level more quickly. Maxium IV rate 60 mg/min.
- Insomnia: 100 to 320 mg IM/IV;
- Convulsions: 100 to 320 mg IV. Repeat if needed (maximum, 600 mg per day);
- Status Epilepticus: 10 to 20 mg/kg IV. Repeat if needed.
🔹 Interaction
The concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects.
🔹 Contraindications
Phenobarbital is contraindicated in patients with known Phenobarbital sensitivity or a history of latent porphyria.
🔹 Side Effects
The most common adverse reaction is somnolence. Other less frequent adverse reactions are agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thinking abnormality, apnea, bradycardia, hypotension, nausea, vomiting and constipation.
🔹 Pregnancy & Lactation
Pregnancy Category D. Phenobarbital can cause fetal damage when administered to a pregnant woman. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be in risk of the potential hazard to the fetus. Caution should be taken when Phenobarbital is administered to a nursing woman since small amounts of Phenobarbital are excreted in the milk.
🔹 Precautions & Warnings
Tolerance and psychological and physical dependence may occur with continuing use. Phenoson should be administered with caution to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse. In patients with hepatic damage, Phenoson should be administered with caution and initially reduced doses.
🔹 Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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Jayson Pharmaceutical Ltd.
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💡 Frequently Asked Questions
Phenoson is indicated for the following conditions:
Sedatives
Hypnotics for the short-term treatment of insomnia
Pre-anesthetics
Long-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures. And, in the em...
Suggested doses of Phenobarbital for specific indications are as follows:Pediatric Oral Dosage:
Preoperative: 1 mg to 3 mg/kg.
Anticonvulsant: 1 mg to 6 mg/kg per day
Adult Oral Dosage:
Daytime sedative: 30 mg to 120 mg daily in 2 to 3 divi...
The most common adverse reaction is somnolence. Other less frequent adverse reactions are agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thin...
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