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Piratam

Tablet

🧬 Piracetam 🏢 General Pharmaceuticals Ltd.
Generic Name Piracetam
Strength 800 mg
Manufacturer General Pharmaceuticals Ltd.
Unit Price Unit Price: ৳ 6.04 (4 x 10: ৳ 241.60) Strip Price: ৳ 60.40
Unit Price: ৳ 6.04 (4 x 10: ৳ 241.60) Strip Price: ৳ 60.40 ✅ In Stock per unit · Bangladesh
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🔹 Indications

🔹 Dosage & Administration

Adults:
  • In cerebrocortical insufficiency disorders: the usual dose is 800 mg 3 times a day.
  • In myoclonic seizures: a dose of 7.2 gm daily, increasing by 4.8 gm per day every 3 to 4 days up to a maximum of 20 gm daily, given in 2 or 3 divided doses.
Children: The daily dosage depends on the weight of the child, 50 mg/kg of body weight in 3 divided doses. Once the desired results have been obtained, reduce the initial dose by half.

🔹 Interaction

In a single case, confusion, irritability and sleep disorders were reported in concomitant use with thyroid extract. At present, no interaction has been observed with the following anti-epileptic drugs, clonazepam, carbamazepine, phenyton, phenobarbitone and sodium valporate, based on a small number of studies.

🔹 Contraindications

Piracetam is contra-indicated in patients with severe renal insufficiency (creatinine clearance < 20 ml/min) and hepatic impairment. As the principal route of elimination for Piracetam is via the kidney, special care must be taken when treating patients known to suffer from renal insufficiency. Monitoring of renal function is recommended in such cases. The increase in half-life is directly related to the decrease in renal function and creatinine clearance. This is also true for the older patient in whom creatinine clearance is dependent on age. When the creatinine clearance is <60 ml/min, or serum creatinine is >1.25 mg/100 ml, the dosage prescribed should be calculated as follows:
  • CrCl 60-40 ml/min: Dosage should be 1/2 of normal dose
  • CrCl 40-20 ml/min: Dosage should be 1/4 of normal dose

🔹 Side Effects

The side effects reported include nervousness, agitation, irritability, anxiety and sleep disturbances. The incidence of these during clinical trials was ( 5% ) and they were more often noted in the older patients taking > 2.4 gm daily. In the majority of cases, a dose reduction sufficed to make these symptoms disappear. Some patients may complain of fatigue or drowsiness, gastrointestinal problems, e.g. nausea, vomiting, diarrhoea and stomachache have also been reported but their incidence during clinical trials was ≤ 2%. Other symptoms e.g. vertigo, headaches, trembling and sexual stimulation have occasionally been reported. Overdose: Piratam appears to be devoid of toxicity even at very high doses and, therefore, the need for specific measures to be taken in case of an overdose is avoided. Drug Interactions: In a single case, confusion, irritability and sleep disorders were reported in concomitant use with thyroid extract. At present, no interaction has been observed with the following anti-epileptic drugs, clonazepam, carbamazepine, phenyton, phenobarbitone and sodium valporate, based on a small number of studies.

🔹 Pregnancy & Lactation

Piracetam should not be prescribed during pregnancy or when breast feeding, except under exceptional circumstances. Piracetam is able to cross the placenta.

🔹 Storage Conditions

Store in a cool and dry place at a temperature below 30˚C, Keep away from sunlight. Keep out of the reach of children.

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💡 Frequently Asked Questions

Cerebral vascular accidents and cerebral insufficiencies: Ischaemic or even hemorrhagic acute accidents, chronic manifestations of the above accidents or of cerebral atherosclerosis. Mental retardation in children: Ease of resuming individual contact...
Adults: In cerebrocortical insufficiency disorders: the usual dose is 800 mg 3 times a day. In myoclonic seizures: a dose of 7.2 gm daily, increasing by 4.8 gm per day every 3 to 4 days up to a maximum of 20 gm daily, given in 2 or 3 divided dos...
The side effects reported include nervousness, agitation, irritability, anxiety and sleep disturbances. The incidence of these during clinical trials was ( 5% ) and they were more often noted in the older patients taking > 2.4 gm daily. In the majori...

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